Online ISSN: 2149-3189
2015
Monthly
Nicaea Medical Publishing
Türkiye

Low-grade fibromyxoid sarcoma: a rare condition with high proliferation

Marzieh Karimi Khezri, M. Özgür Taşkapılıoğlu, Alper Türkkan, Ulviye Yalçınkaya, Ahmet Bekar
  • Marzieh Karimi Khezri (Author) Uludag University, School of Medicine Department of Neurosurgery
  • M. Özgür Taşkapılıoğlu (Author) Uludag University, School of Medicine Department of Neurosurgery https://orcid.org/0000-0001-5472-9065
  • Alper Türkkan (Author) VM MedicalPark Hospital, Department of Neurosurgery
  • Ulviye Yalçınkaya (Author) Uludag University, School of Medicine, Department of Surgical Pathology
  • Ahmet Bekar (Author) Uludag University, School of Medicine Department of Neurosurgery
DOI
https://doi.org/10.18621/eurj.339764
Abstract
Low-grade fibromyxoid sarcoma (LGFMS) is a type of high metastatic potential of the fibrosarcomas. Most of the time there is a long interval between tumor presentation and metastasis. We present 2 cases of LGFMS. The first is a 31-year-old female with a mass in anterior aspect of her left thigh, and the other is a 68-year-old female with mass in posterior of her neck. Both cases underwent operation for several times and confirmed as LGFMS histopathologically, there is no exact protocol for postoperative follow-up to detect early metastases according to the relative variety of LGFMS. So informing the patients about the long-standing metastatic potential of their disease is important. 
Keywords
fibrosarcoma, low-grade fibromyxoid sarcoma, surgery
References

[1] Evans HL. Low-grade fibromyxoid sarcoma. A report of two metastasizing neoplasms having a deceptively benign appearance. Am J Clin Pathol 1987;88:615-9.

[2] Folpe A, van den Berg E, Molenaar WM. Low grade fibromyxoid sarcoma. In: Fletcher CDM, Unni KK, Mertens F (eds). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press: Lyon, 2002, pp. 104-5.

[3] Steiner MA, Giles HW, Daley WP. Massive low-grade fibromyxoid sarcoma presenting as acute respiratory distress in a 12-year-old girl. Pediatr Radiol 2009;39:396-9.

[4] Wu X, Petrovic V, Torode IP, Chow CW. Low grade fibromyxoid sarcoma: problems in the diagnosis and management of a malignant tumour with bland histological appearance. Pathology 2009;41:155-60.

[5] Goodlad JR, Mentzel T, Fletcher CD. Low grade fibromyxoid sarcoma: clinicopathological analysis of eleven new cases in support of a distinct entity. Histopathology 1995;26:229-37.

[6] Folpe AL, Lane KL, Paull G, Weiss SW. Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes: a clinicopathologic study of 73 cases supporting their identity and assessing the impact of high-grade areas. Am J Surg Pathol 2000;24:1353-60.

[7] Saito R, Kumabe T, Watanabe M, Jokura H, Shibuya M, Nakazato Y, et al. Low-grade fibromyxoid sarcoma of intracranial origin. J Neurosurg 2008;108:798-802.

[8] Kim SY, Kim M, Hwang YJ, Han YH, Seo JW, Kim YH, et al. Low grade fibromyxoid sarcoma CT, sonography, and MR findings in 3 cases. J Thorac Imaging 2005;20:294-7.

[9] Fujii S, Kawawa Y, Horiguchi S, Kamata N, Kinoshita T, Ogawa T. Low-grade fibromyxoid sarcoma of the small bowel mesentery: computed tomography and magnetic resonance imaging findings. Radiat Med 2008;26:244-7.

[10] Mohamed M, Fisher C, Thway K. Low-grade fibromyxoid sarcoma: Clinical, morphologic and genetic features. Ann Diagn Pathol 2017;28:60-7.

[11] Rakheja D, Seaward JR, Timmons CF. Low-grade fibromyxoid sarcoma with striking zonation. Int J Surg Pathol 2017:1066896917742724.

There are 11 references in total.
How to Cite
1.
Karimi Khezri M, Taşkapılıoğlu M Özgür, Türkkan A, Yalçınkaya U, Bekar A. Low-grade fibromyxoid sarcoma: a rare condition with high proliferation. Eur Res J. 2018;4(3):238-241. doi:10.18621/eurj.339764
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Vol. 4 No. 3 (2018)

Article Information

  • Article Type Case Report
  • Submitted February 21, 2026
  • Published July 3, 2018
  • Issue Vol. 4 No. 3 (2018)
  • Section Case Report
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