Is there a difference in 25-hydroxyvitamin D levels between female university students with and without joint hypermobility?
Methods: In this cross-sectional, descriptive and case-control study, 76 female participants aged 18-25 years were included. The Beighton score with a cut-off of 4/9 was applied for defining GJH. In addition, serum biochemical (the enzymatic colorimetric method) and hormonal (the electrochemiluminescence method) parameters were evaluated.
Results: The mean serum 25-hydroxyvitamin D (25[OH]D) levels of GJH (n = 38) and non-GJH (n = 38) groups were 15.70 ± 7.96 ng/mL and 16.80 ± 5.45 ng/mL, respectively. There was no statistically significant difference between the groups in terms of biochemical and hormonal parameters. We found vitamin D deficiency in 89.5% of participants with GJH, and 84.2% of controls. There was no correlation between vitamin D, Brighton criteria, and musculoskeletal complaints.
Conclusion: The female participants with GJH showed similar frequency of musculoskeletal complaints and similar low level of 25(OH)D in relation to controls.
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Article Information
- Article Type Research Article
- Submitted February 21, 2026
- Published July 3, 2019
- Issue Vol. 5 No. 4 (2019)
- Section Research Article
