May cyproheptadine be a treatment choice for prophylaxis of PFAPA syndrome?

Authors

Arzu Ekici
https://doi.org/10.18621/eurj.666806
No abstract available.
PFAPA syndrome, periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis

1. Feder HM, Salazar JC. A clinical review of 105 patients with PFAPA (a periodic fever syndrome). Acta Paediatr 2010;99:178-84.

2. Thomas KT, Feder HM Jr, Lawton AR, Edwards KM. Periodic fever syndrome in children. J Pediatr 2013;135:15.

3. Stojanov S, Hoffmann F, Kéry A, Renner ED, Hartl D, Lohse P, et al. Cytokine profile in PFAPA syndrome suggests continuous inflammation and reduced anti-inflammatory response. Eur Cytokine Netw 2006;17:90-7.

4. Müller T, Dürk T, Blumenthal B, Grimm M, Cicko S, Panther E, et al. 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo. PLoS One 2009;4:e6453.

5. Taniguchi K, Ono N, Sakai T, Ichiyama Y, Uemichi K. Response to cimetidine in a 1-year-old child with PFAPA syndrome. Turk J Pediatr 2016;58:687-9.

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Article Information

  • Article Type Letter to the Editor
  • Submitted February 21, 2026
  • Published May 3, 2020
  • Issue Vol. 6 No. 3 (2020)
  • Section Letter to the Editor
  • File Downloads 1038
  • Abstract Views 233
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