Online ISSN: 2149-3189
2015
Monthly
Nicaea Medical Publishing
Türkiye

Use of del Nido cardioplegia in adult cardiac surgery

Bişar Amaç, Mümün Selçuk, Semra Bölükbaş, Fatma Kahraman, Ahmet Kağan As, Muhammed Savran, Orhan Güvenç, Mehmet Tuğrul Göncü, Mesut Engin, Senol Yavuz
  • Bişar Amaç (Author) Department of Cardiovascular Surgery, Division of Perfusion, University of Health Sciences, Mehmet Akif İnan Training and Research Hospital, Şanlıurfa, Turkey https://orcid.org/0000-0003-0320-4239
  • Mümün Selçuk (Author) Department of Cardiovascular Surgery, Division of Perfusion, University of Health Sciences, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey https://orcid.org/0000-0001-8635-0463
  • Semra Bölükbaş (Author) Department of Cardiovascular Surgery, Division of Perfusion, University of Health Sciences, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey https://orcid.org/0000-0001-5042-6075
  • Fatma Kahraman (Author) Department of Cardiovascular Surgery, Division of Perfusion, University of Health Sciences, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey https://orcid.org/0000-0001-9250-3761
  • Ahmet Kağan As (Author) Department of Cardiovascular Surgery, University of Health Sciences, Bursa Medical Faculty, Bursa Yüksek İhtasas Training and Research Hospital, Bursa, Turkey https://orcid.org/0000-0001-8098-4393
  • Muhammed Savran (Author) Department of Cardiovascular Surgery, Ağrı State Hospital, Ağrı, Turkey https://orcid.org/0000-0003-2688-6930
  • Orhan Güvenç (Author) Department of Cardiovascular Surgery, Bursa Uludağ University, Medical Faculty, Bursa, Turkey https://orcid.org/0000-0003-1072-1269
  • Mehmet Tuğrul Göncü (Author) Department of Cardiovascular Surgery, University of Health Sciences, Bursa Medical Faculty, Bursa Yüksek İhtasas Training and Research Hospital, Bursa, Turkey https://orcid.org/0000-0002-3666-8673
  • Mesut Engin (Author) Department of Cardiovascular Surgery, University of Health Sciences, Bursa Medical Faculty, Bursa Yüksek İhtasas Training and Research Hospital, Bursa, Turkey https://orcid.org/0000-0003-2418-5823
  • Senol Yavuz (Author) Department of Cardiovascular Surgery, University of Health Sciences, Bursa Medical Faculty, Bursa Yüksek İhtasas Training and Research Hospital, Bursa, Turkey https://orcid.org/0000-0001-5246-0808
DOI
https://doi.org/10.18621/eurj.970465
Abstract
In most adult cardiac surgery operations, the heart must be completely immobile and isolated from the blood. Therefore, the heart is stopped in diastole and a still operative site is obtained. Cardiac arrest results in ischemia-reperfusion injury. For these reasons, myocardial protection and the prevention of damages are required. Various cardioplegia solutions are used for this purpose. It can be said that cardioplegia is the gold standard method of myocardial protection in cardiac arrest. Nowadays, "Single-dose cardioplegia" applications are increasingly used, especially in minimally invasive cardiac surgery and basic coronary bypass procedures due to the advantages they provide, which include reduction of aortic cross-clamp time, prevention of frequent interruption of the procedure due to cardioplegia, and reduced postoperative myocardial dysfunction incidence. The two main solutions used in single dose cardioplegia applications are the Bretschneider solution and the del Nido extracellular cardioplegia solution. The del Nido cardioplegia solution (dNCS), which was originally developed for use in pediatric cardiac surgery, has recently increased its use in adult cardiac surgery due to straightforward application and long-term effectiveness. The del Nido cardioplegia reduces the aortic cross clamp duration, cardiopulmonary bypass time and required cardioplegia solution volume, and is a safer and superior cardioplegia solution and technique in terms of myocardial protection with regards to many organs and cardiac-biochemical parameters.
Keywords
Del Nido Cardioplegia, Adult Cardiac Surgery, Myocardial Protection, Cardioplegia, Cardiopulmonary Bypass
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How to Cite
1.
Amaç B, Selçuk M, Bölükbaş S, et al. Use of del Nido cardioplegia in adult cardiac surgery. Eur Res J. 2022;8(1):139-144. doi:10.18621/eurj.970465
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